Biological membranes consist of lipids, proteins and carbohydrates to define the
compartmentalization of the cells. Membranes are also very dynamics not only within the
lateral and in the transverse direction of lipid bilayers, but also undergo constant motions
and contacts in the intracellular cytoplasma of the cells. Recent progress in the
structures/dynamics and crowdedness (or clustering) of these membrane components has
allowed us to address how the molecular diversity and interactions of these essential
cellular components help in exert its membrane functions through channels, transporters,
enzymes, receptors and other related structural components of lipid and glycoconjugates. In
order to achieve this goal, we will spend 1/3 of the lecture hours to review the basics of
membrane structures and functions, another 1/3 to update the progress in the field based
on the review articles during the last couple years and finally, the last 1/3 to guide students
reading the state of the art publications in the field of membrane biology.
吳文桂 Wen-guey Wu 教授
生物膜由脂質、蛋白質和碳水化合物組成,定義細胞的區室化。
膜不僅在脂質雙層的橫向和橫向上也非常動態,而且在細胞的細胞內細胞質中也經歷不斷的移動和接觸。
這些膜成分的結構/動力學和擁擠度(或聚類)的
最新進展使我們能夠解決這些重要細胞成分的分子多樣性和相互作用
如何透過通道、轉運蛋白、酶、受體和其他相關蛋白質幫助發揮其膜功能。
為了實現這個目標,我們將用1/3的講課時間回顧膜結構和功能的基礎知識,
另外1/3的時間根據過去幾年的綜述文章更新該領域的進展,
最後,最後1/3引導學生閱讀膜生物學領域最先進的出版品。
本課程尚未有人來評價
<span style="font-size:12.0pt;font-family:'新細明體',serif;">本課程將介紹生物膜的結構、功能及動態性。 細胞膜由蛋白質、細胞蛋白質和碳水化合物組成,對細胞進行不同的區域,並涉及多種生物過程。在細胞內部不斷與其他細胞器進行接觸與交流。</span>